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Unlike injectable formulations that typically require cold-chain storage, oral GLP-1RAs bypass refrigeration constraints, thereby reducing manufacturing and distribution costs and improving accessibility in resource-limited settings [73]
The SCALE Kids trial addresses this unmet need to research effective and safe chronic weight loss treatment for this age group6
Higher doses tend to produce stronger effects on appetite regulation and metabolic activity, although individual outcomes vary
however, the graphic indicates that GLP1s/SGLT2s are actually Causal, when the inverse is true
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